There is limited clinical trial experience with desvenlafaxine succinate overdosage in humans. Please choose the category that best describes you. 2023 Inside Rx, LLC. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Latest Facts on COVID-19 Vaccine Boosters, History Does Repeat: Vaccine Resistance Is Not New, Synthetic Chemical in Many Products Linked to Early Death, New Drug for Early Breast Cancer: First Advance in 20 Years, Love Horror? In fact, most people will feel fuller after meals and between themhelping you eat and snack less. Concomitant use of PRISTIQ with other serotonergic drugs increases the risk of serotonin syndrome. *Average savings based on usage and Inside Rx data as compared to cash prices; average savings for all generics are 78%; 37% for select brand medications; restrictions apply. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. Remember - drug interactions are usually preventable with your proactive efforts. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 2023 Jan 5;7:e40062. Three capsules taken orally twice daily before lunch and dinner, Immediate, unlimited access to all AFP content, Immediate, unlimited access to this issue's content. To avoid impact on the absorption of medications: For all medications that should be taken with food, take them after starting a meal. Epub 2018 Nov 13. Our Plenity (cellulose and citric acid) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Yes, Plenity contains neither wheat nor gluten. If you miss a pre-meal dose, take Plenity with 16 oz. Common side effects of Plenity are mild and include: abdominal distension, abdominal pain, bloating, irregular bowel movements, changes in frequency and This tool explains what the interaction is, how it occurs, the level of significance (major, moderate, or minor) and usually a suggested course of action. Closely monitor for bleeding for patients receiving an antiplatelet or anticoagulant drug when PRISTIQ is initiated or discontinued, Drugs that are Primarily Metabolized by CYP2D6. It is an FDA-cleared medical device available only by prescription. For the safe and proper use of Plenity or more information, talk to a healthcare professional, read the Patient Instructions for Use, or call 1-844-PLENITY. Developed, clinically tested, and manufactured by Gelesis. Reduce the dose of these drugs by up to one-half if co-administered with 400 mg of PRISTIQ. Cochrane Database Syst Rev. People taking Plenity were more likely to experience GI issues diarrhea, bloating, abdominal pain, and gas than people taking the placebo, but the percentages were quite similar. Plenity is a unique nonsurgical device for weight management in overweight and obese adults (tested on participants with a body mass index of 27 to 40 kg per m2) in conjunction with diet and exercise.1 Plenity is available in capsule form, but it is not considered a drug because it is not absorbed by the body. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. monograph. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Obesity, Mechanism of Actionhydrated hydrogel particles mix w/ ingested food, creating larger volume w/ higher elasticity and viscosity in the stomach and small intestine, promoting satiety and fullness. It undergoes rigorous internal medical review and is updated regularly to reflect new information. Since most people do not know if two or more drugs could interact, it's important to check the status of drug interactions with each new drug. Plenity has not been studied in people under the age of 22. Being proactive in your own health, checking for drug interactions, and discussing concerns with your healthcare provider can be a life-saving task. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Age restrictions may apply to the purchase of certain drugs. Our scientific content is evidence-based, scientifically balanced and non-promotional. To describe the mechanism, clinical trial data, adverse effects, and potential role in therapy of an oral superabsorbent hydrogel (OSH) for weight management. It is currently approved by the U.S. Food and Drug Administration. Relevance to patient care and clinical practice: WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. It's always best to ask your healthcare provider for the latest information on drug interactions. Not all drug interactions are bad. US-PLEN-2000613 The following adverse reactions are discussed in greater detail in other sections of the label. US-PLEN-2100031 Contact a doctor right away if problems occur. Plenity (cellulose and citric acid) is an oral capsule that promotes fullness and may help to increase satiety to help patients manage their weight and is indicated to aid in weight management in overweight and obese adults with a Body Mass Index (BMI) of 25-40 kg/m2, when used in conjunction with diet and exercise. Pricing shown online or via the Inside Rx app are subject to change in real time. Would you like email updates of new search results? Within 14 days of stopping an MAOI intended to treat psychiatric disorders. ( 1) Affect how your medication works by changing levels of the drug in your blood, Put you at risk for side effects and toxicity. To calculate your BMI, divide your weight in pounds (lb.) WebMD does not provide medical advice, diagnosis or treatment. Only human studies were used for drug interaction, efficacy, and safety data. INSIDE RX IS NOT INSURANCE. Links to sites outside of Pfizer Medical Information are provided as a resource to the viewer. If you miss a pre-meal dose, take Plenity with 16 oz. Careers. It has been cleared by the FDA for adults. Plenity may affect how well your body absorbs other medications. The site is secure. 2023 Pfizer Inc. All rights reserved. The hydrogel is partially broken down by enzymes once in the large intestine, and it loses its three-dimensional structure and most of its absorption capacity. This interaction can occur with the commonly used statins to lower cholesterol, like atorvastatin, lovastatin, or simvastatin. FOIA A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. WebOnly human studies were used for drug interaction, efficacy, and safety data. Get everything Plenity offers for just $1.75 per meal. However, you can also use our online drug interaction checker to learn more about possible drug interactions, too. In both treatment groups, most (>95%) adverse events were assessed by the investigator as mild or moderate in intensity. If you have any further questions about your Plenity prescription, please refer to our Important Safety Information below or speak with your healthcare provider. Patients who are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide should not take Plenity. 8600 Rockville Pike Learn more about price differences between brand and generic drugs. cellulose/ citric acid hydrogel For a full list of Inside Rx program terms see full terms or call 800-722-8979. How much weight can I expect to lose while taking Plenity? This information might be about you, your preferences or your device. Patients should take three capsules twice per day with 500 mL of water 20 minutes before lunch and dinner. This product's label may have been updated. Rx Only. You can either ask your healthcare provider about Plenity, or visit MyPlenity.com to start a telehealth experience with a licensed physician. In a single clinical trial of 436 patients, there were no differences in rates of adverse effects between those taking Plenity (n = 223) and those taking placebo (n = 213). False-positive urine immunoassay screening tests for phencyclidine (PCP) and amphetamine have been reported in patients taking desvenlafaxine. Plenity is taken as three capsules with 16 ounces (2 glasses) of water 20 minutes before lunch and dinner. Disclaimer. OSH functions primarily through space occupancy in the stomach and small intestine. This content is owned by the AAFP. Table 8: Clinically Important Drug Interactions with PRISTIQ Pristiq Website for Healthcare Professionals. Inside Rx cannot be used with any insurance benefit, copay assistance programs, or by persons covered by state-funded or federal-funded programs such as Medicare, Medicaid, or Tricare for purchases of certain medications, even if processed outside the benefit as an uninsured (cash-paying) patient. WebDrug-drug interactions can decrease how well your medications work, may increase minor or serious unexpected side effects, or even increase the blood level and possible toxicity Some mixtures of medications can lead to serious and even fatal consequences. Usually, your doctor and pharmacist will have already done this with your prescription medications, but it's a good idea to double check and learn about these medications yourself. The capsules contain particles that rapidly absorb water in the stomach, creating small individual gel pieces with the texture of plant-based foods such as vegetables, without having any caloric value. Plenity passes through the digestive system, maintaining its three-dimensional structure in the stomach and small intestine before breaking down in the colon. Plenity should not be prescribed for pregnant patients or those with a history of strictures, esophageal anatomic anomalies, or complications from prior gastrointestinal surgery. All rights reserved. They will understand the significance of the interaction, and will be able to recommend the next best steps you should take. Worsen a medical condition you may already have. WebSignificantly more patients treated with Plenity (59% vs. 42% with placebo) achieved a weight loss of at least 5%, and 27% (vs. 15% with placebo) lost at least 10% of their body 2019 Feb;27(2):205-216. doi: 10.1002/oby.22347. Skip to main content Price a Medication Get Savings Card Help A few simple additions or swaps can help you feel fuller and more satisfied. STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. No serious adverse effects were observed in the patients taking Plenity.1 Hypersensitivity to any component of the formulation is a contraindication. Requests for samples of prescription medications can be made by contacting Pfizer for Professionals at 1-800-505-4426 or by visiting the PfizerPro website www.pfizerpro.com. Available for Android and iOS devices. Save 15% when you purchase a 12-week supply ($249/$1.48 per meal). No. We work directly with manufacturers and pharmacies to find you lower prices on thousands of prescription medications. This information is currently not available for this drug. For instance, a person who is 200 lb. The recommended dose for PRISTIQ is 50 mg once daily, with or without food. In order to provide you with relevant and meaningful content we need to know more about you. Treatment for: Weight Loss (Obesity/Overweight). Plenity is indicated to aid weight management in adults with excess weight or obesity, a Body Mass Index (BMI) of 2540 kg/m, when used in conjunction with diet and exercise. Recent advances in therapies utilizing superabsorbent hydrogel technology for weight management: A review. Take Plenity with 16 ounces ( 2 glasses ) of water 20 minutes lunch. Been cleared by the U.S. Food and drug Administration licensed physician medical review and is updated regularly to new... Like email updates of new search results like atorvastatin, lovastatin, or simvastatin with and... Prices on thousands of prescription medications can be made by contacting Pfizer Professionals... And updates ( 2 glasses ) of water 20 minutes before lunch and dinner a pre-meal dose, take with! Information is currently not available for this drug Inside Rx program terms see full or... Information might be about you content is evidence-based, scientifically balanced and non-promotional citric acid hydrogel for a full of! Patients taking Plenity.1 Hypersensitivity to any component of the interaction, efficacy, and data. The investigator as mild or moderate in intensity for weight management: a review cholesterol! Human studies were used for drug interactions, and discussing plenity drug interactions with your proactive.. 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