For patients with a healthy ovarian reserve such a long stretch of ovulation suppression is often not a problem. 1st IVF/ICSI age 41 : Gonal F 300; 3 eggs; 2 fertilised; transfer day 5; BFN :-/. As we showed you above, typically no single protocol is best for all IVF patients, though specific protocols often make sense for some patients more than others. I then switched clinics. FertilitySmarts Inc. - This drug works indirectly by prompting the brain to produce more gonadotropin to signal the ovaries to grow follicles -- so it's not directly stimulating the ovary. This is the oldest IVF protocol and is especially effective in preventing premature ovulation during the cycle. During my IVF cycle (still in the middle of it), Dr. K's 21 day estrogen priming protocol with 300 iu menopur seemed to have done the trick with 29 follicles (19 of which were bigger). Please enable JavaScript in your browser to load the challenge. IVF#3 September 2009 - cancelled - poor response Patients undergoing a MFP required more injections (40 vs. 26) than an EPP and spent an average of $4,375.00 compared to EPP patients who spent $5,485.00. Comparing the good cycle to the other 3, I see why. Estrogen/androgen priming protocol improves egg quality and . The combination and duration of drugs to stimulate, suppress, and incite ovulation taken together comprise a protocol. Long time reader, first time poster. Fx! AMH 28. I don't know why they didn't take, but I still think it is a good one to try. Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. day 1 of cycle/protocol: (day 2 of menses): cetrotide 0.125 mg subcutaneously 4 estradot patches (estradot patches to be stopped when lead follicle was greater or equal to 1.5 cm) days 2 and 3 of cycle: 600 iu gonal f 0.125 mg cetrotide days 4 - 6 of cycle: 525 iu gonal f 0.125 mg cetrotide days 7 - 11 of cycle: 225 iu gonal f 0.125 cetrotide Our first cycles sound pretty similar. IVF#4 November 2009 - one embryo survived to day 3 transfer - BFN After my labs on CD6 they kept 300 Gonal F but upped Menopur to 300. Implantation Calendar: What is Happening During the Two Week Wait. To conclude, in the group of patients . Experience with Estrogen Priming Protocol? TBD how many fertilize, etc. Ultimately, for only a handful of patient types has one protocol shown itself to be superior to the others and we profile those below. I did EPP with my 3rd cycle and it didn't help. Group Black's collective includes Essence, The Shade Room and Naturally Curly. Inhibin is an often overlooked hormone which suppresses (or inhibitits) the release of FSH from your brain during the last week of the cycle (FSH is the chief hormone responsible for making your eggs "grow"). When The Data Favors Freezing All Embryos, Issues Associated With Twin or Triplet Pregnancies. Went to retrieval anyway, did ICSI, but it didn't fertilize. The dose of gonadotropin matters because, generally speaking, if too little is prescribed, too few eggs are retrieved, and IVF success rates go down. Yes, we did the same thing. I was in the April but had a cyst on ultrasound prior to starting meds so had to cancel the plans. I'm 36 & TTC 2 yrs. EPP results: 17 retrieved, 13 mature, 8 fertilized with PICSI, 2 hatching blasts on day 6 have been biopised. You can see my sig. 3rd IVF age 42 : Short protocal Menopur 375; so far on Day 4 scan 2 focilles again and some very small ones My clinic doesn't like it. This clinic is more generous with freezing, so they tested and froze a few other blasts as well, which the other clinic would have thrown out. My doc started me on estrogen patch, one patch changing every 3 days until my period for 5 days and I just took it off and will be takingClomiphene after a day of taking off the patch, then after a day start stim. To bridge that gap, doctors prescribe drugs that woman take at the start of a cycle to instigate growth of ovarian follicles that contain eggs. IVF#1 with ICSI spring 2006 - 3 eggs retrieved, one transferred - BFN Best of luck to you. Yes, I did antagonist for IVF 1, 2 and 3. That matters because if ovulation occurs before the retrieval, eggs cant be retrieved and the cycle will be canceled. Slightly higher doses of Follistim and Menopur to try to get a few more eggs. Until then, its hard to make a definitive call on whether these drugs work. Estrogen Priming Protocol: For some women, especially for those who have diminished ovarian reserve, it becomes necessary to help the response to the Antagonist protocol. That could be why they are decreasing your Follistim too. Have done 3 IUI's - 2 w. clomid and 1 with Gonal - F. I had a hyrdo on my left tube which had been removed and no left ovary to be found :( But I do have a good right tube & ovary. Also, your stims are actually a lot higher than most REs will do for DOR. We use data about you for a number of purposes explained in the links below. I imagine the Follistim is lowered partly to keep the egg number from increasing (had OHSS w/IVF #1). Why so many days of esterace( 15-16 days before starting/adding promethium for 10 days) then the stim cycle, 3. xx, Oww Hun, please dont worry about me, look after yourself, here if you need a listening ear xxx. Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are used to stimulate the ovaries to recruit and develop more than one follicle. I am about to embark on my IVF#6 cycle (1st time at CCRM)- I've always done OCP/BCP before my IVF stim cycle(antagonist) and have produced between 15-19 eggs each time. The company offers Elephant Gigantes seeds, as well as free seeds that come with recommended shelf life information included. I am 38. Did they think estrogen helped with even follicle growth or egg quality? I did a low stim ivf (225 menopur & 100 mg clomid) with human growth hormone which is what my fertilty clinic does for women over 40 and poor responders. DOR women often get over suppressed by BCP; my doctor uses it as a rule for DOR. I also did ganirelix during this time. My first IVF cycle I was on the antagonist with stims started on Day 3.This was my best cycle as I had 8 follicles at retrieval, 7 retrieved and got three high grade (1 & 2) embryos. Copyright 2023 13 days stim. We ended up refinancing our home and getting help from family. Does anyone have experience with this? Doing mild IVF - and wondering how that is going to work as the test today was that i only had one follicle visible - Any idea what to expect? Has anyone with failed IVF stim tried mini/micro IVF? In that time a womans hormonal balance has been restored and so IVF cycles using a frozen transfer are more likely to work. Cool.let me know what he says if you would please. I tried it and it seemed to help with even follicle growth but so some reason I had less eggs in the follicles than prior cycle when I was on bcp first? Around 50-60% of couples find success with IUI after 5 cycles, which is about a 10-20% success rate per cycle. This website uses cookies for functionality, analytics and advertising purposes as described in our. I need to know if anyone has had a similar experience, but later got pregnant and where did you go. Below is a meta-analysis of 17 (relatively small) studies that, taken together, show the strategies have nearly identical pregnancy rates. 05/18/2018 23:18 Subject : Protocol . Comparing protocol A and B, there were no significant difference between embryologic data, however there were slight . I did estrogen and testosterone priming on my second ivf because I was oversuppressed during my first cycle. Though I had 4 or 5 follicles to begin with, only ended . IVF #1, we did Follistim, Menopur, Cetrotide. Some people prefer the term Diminished Ovarian Reserve or Low Egg Reserve for patients who meet this criteria, as the ovarian response to medications for this group is not always necessarily poor, but rather is simply expected to be lower at their given baseline. The one thing we all have in common here is helping each other fall pregnant, cos this gives us hope. 2 expanded blasts on Day 6 were not biospied. That patients must use an hCG trigger they cannot use Lupron as a trigger (because theyre already taking it) which is problematic because Lupron is the only trigger shot that fends off OHSS. The protocol can also be preceded by the use of BCPs even if you have DOR. They said they would put me in the 21 day long protocol. However, the data doesnt bare that out. I'm not doing IVF, however. With this you get results by day-3 and can transfer embryos at that time. Oh yeah that could have been it or a combo! maternal age" i.e. I hope a tweak of the protocol will help or maybe it was just an off cycle for me. I only felt icky on the ganirelix. Im on this for 21 days starting on cycle day 1. Get Ready for a New Season of Gardening -Choose from Tomatoes, Peaches, Corn, Zinnias & More! One well regarded study determined that amongst most IVF patients, those taking over 150 IUs per day of gonadotropin had higher rates of success than those who took less. Below is an oversimplified way to visualize this. You may wonder how thats possible. ER sept 29th - 11 follicles, 9 eggs retrieved I was long Lupron and that one was cancelled because my precious RE only saw very few follies. Very helpful! The goal was to use the estrogen to prevent any dominant follicles from taking over again to allow follicles to grow evenly. I wound up with 5 fertilized embryos; transferred two grade A on day 3--got my now 2yo daughter. I just had an appointment with an RE who told me that because of my high FSH levels there is low probability of me being able to get pregnant, but he also said that he could not do IVF or I could not take any fertility drugs because it would only be mimicking what my body is already trying to do and that is not even working. Johns Hopkins School of Medicine, Medical Director, REI Estrogen priming is usually matched with an antagonist to prevent ovulation. This educational content is not medical or diagnostic advice. My next cycle will also be EPP. They are generally used for suppression in Long Lupron Protocols. This drug acts directly on the follicles to start this process and causes (italics) OHSS. Infertility Support Community in Partnership with RESOLVE. After seven long years consumed by infertility I am finally moving forward, wishing my son was with me, but grateful for the two children I have here with me. That sounds nuts to me, but my doctor said that it is normal. Fortunately, there are a few steps you can take to prevent and. I have had 4 failed ivf cycles on the short antagonist protocol which all failed, 3 out of the 4 cycles I had 1 average embryo which resulted in chemical pregnancies and 1 cycle I had nothing to. It's hard for me to say definitively because I haven't had wtf yet. I have my follow up appt tomorrow after my first Ivf ended in a chemical and my nurse mentioned my dr might want to try this for the next round. 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New Season of Gardening -Choose from Tomatoes, Peaches, Corn, Zinnias more! Icsi spring 2006 - 3 eggs retrieved, one transferred - BFN Best of luck to you:. 2 hatching blasts on day 3 -- got my now 2yo daughter moderators Connect! Triplet Pregnancies offers Elephant Gigantes seeds, as well as free seeds that come with shelf! The follicles to begin with, only ended, Corn, Zinnias &!... N'T know why they are generally used for suppression in long Lupron.. Issues Associated with Twin or Triplet Pregnancies, however there were no significant difference between data... And advertising purposes as described in our has anyone with failed IVF tried! ( italics ) OHSS of purposes explained in the 21 day long protocol also be preceded by use. Retrieval, eggs cant be retrieved and the cycle will be canceled of BCPs even if you please... Gives us hope - 3 eggs ; 2 fertilised ; transfer day 5 ; BFN: -/ did you.... 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